March 24, 2022

Thrombogenic Hypothesis of Heart Disease- Part 1

Articles by Dr. Erdman are for informational purposes, and are not to be taken as specific medical advice.

 

I’ve been telling you for years that cholesterol is not the cause of heart disease, and no drug, aspirin a day regimen or fat restricting diet does a bit of good in lowering heart attack risk or death. The whole saturated fat theory of heart disease was fabricated to begin with, yet it’s been a staple of “modern medicine” for forty years.

Today, I will introduce you to the latest information on what causes heart disease and arterial thickening called atherosclerosis. The thrombogenic hypothesis asserts that blood clotting is the underlying pathological process that causes all heart disease.

Incidentally, once you understand this disease process, then you can also comprehend how both Covid-19 and the Covid jabs can be causing all these heart related issues.

The old theory says if you eat too much saturated fat it gets turned into cholesterol in your blood stream, then it’s absorbed into the arteries and forms narrowing and thickenings. It sounds plausible and has been the working mechanism spouted by doctors for 40 years. The only problem is, it isn’t true.

The following information is pulled from an interview with Dr. Malcolm Kendrick, the author of “The Clot Thickens: The Enduring Mystery of Heart Disease.”

In 1852, a Viennese researcher, Karl Von Rokitansky, developed what he called the “encrustation theory of heart disease.: Today it’s been renamed the thrombogenic hypothesis. Thrombo refers to “blood clots” and genesis means “where it starts.”

Dr. Kendrick states, “We know blood clots cause the final event in cardiovascular disease. We know blood clots cause plaque to grow. Why won’t you accept that blood clots are the thing that starts heart disease in the first place?”

Now, let’s understand the mechanism of injury. Your blood vessels are lined with endothelial cells, like tiles on a wall. These are also covered with a glycocalyx layer similar to the feel of a slippery fish or a coating of Teflon. This is the inside of an artery wall; a very slippery surface allowing easy flow of blood through the opening.

If that endothelial layer is damaged, the body can’t let that go or we would bleed out the artery wall and die. Instead, the body recognizes the damage and sends a clot formation to repair the area. Once a clot forms, it generally does not keep getting bigger and bigger. It is usually covered by endothelial progenitor cells (ones that make endothelial cells) that are always floating in your blood stream. This then forms a fresh layer of tiles (endothelial cells) and the clot is now within the wall of the artery. This is how the wall “thickens” and over time, if damage outpaces repair, can narrow the artery and reduce blood flow!

It is widely accepted with thousands of papers saying that blood clots forming on existing plaque will cause the plaque to grow in size. What mainstream medicine will not accept is that a blood clot on a healthy artery wall can start the process.

Dr. Kendrick notes that the conventional view of LDL cholesterol getting into the arterial wall where it initiates the plaque formation falls apart on close inspection The biggest problem here is that LDL cannot cross the endothelium! Now tell me, if it can’t cross the arterial wall, how does it damage the arterial wall? And how does it then cause plaque formation? It doesn’t and can’t!

The question then becomes, “What causes endothelial lining damage and what can we do to prevent it?”

The worst thing for our arteries is high blood sugar and diabetes. High sugar damages the glycocalyx layer, reducing it by as much as two thirds. Then the endothelial cells are exposed to anything in the blood that can produce cell damage.

The damage to the glycocalyx is why diabetics are prone to arterial and capillary disease. You don’t get plaque buildup in capillaries, they are too small. Instead, they break down and are destroyed, leaving you with poor circulation to the legs and feet, ending in ulcers.

As these capillaries are lost, diabetics get peripheral neuropathies, retinal damage and kidney damage. Blood pressure becomes elevated as the heart works harder to push blood through the clogged network of damaged vessels.

Heavy metals like aluminum and lead cause arterial wall damage. Over the counter NSAIDS like ibuprofen, aspirin and naproxen cause platelet aggregation, making blood clots.

Omega-6 fatty acids found in seed oils and processed foods, called linoleic acid (LA), are worse than sugars.

Stress induces increased blood sugar and blood pressure by increasing cortisol in your body.

And finally, quit smoking! It does horrible damage to your arterial wall linings.

Next week we will look at how the Covid jabs and Covid infection can affect the arterial walls, and what you can do to mitigate damage.